Table 1.

Correlation between ADAM12 expression and clinicopathological parameters of human colorectal cancer.

Parameters		ADAM12 Expression		p-Value
	Total	Negative	Positive
	(n = 366)	(n = 201)	(n = 165)
Age (years)				0.229
<61.4	159	93	66
≥61.4	207	108	99
Sex				0.079
Male	220	129	91
Female	146	72	74
Tumor size (cm)				0.733
<4.9	201	112	89
≥4.9	165	89	76
Stage				<0.001
I	45	12	8
II	143	89	54
III	163	78	85
IV	15	5	10
Lymphovascular invasion				0.062
Negative	266	154	112
Positive	100	47	53
Perineural invasion				0.824
Negative	244	135	109
Positive	122	66	56
Histologic type				0.092
WD	127	66	61
MD	191	103	88
PD	30	17	13
Mucinous/Signet ring cell	18	15	3
Depth of invasion (T)				0.026
T1	15	12	3
T2	47	30	17
T3	289	154	135
T4	15	5	10
Lymph node metastasis (N)				0.003
N0	191	119	72
N1-3	175	82	93
Distant metastasis (M)				<0.001
M0	325	189	136
M1	41	12	29

ADAM12, A disintegrin and metalloprotease 12; WD, well differentiated; MD, moderately differentiated; PD, poorly differentiated.