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. 2021 Apr 16;13(8):1933. doi: 10.3390/cancers13081933

Table 2.

Ocular surface complications of 5-fluorouracil for ocular surface squamous neoplasia.

Study Number of Patients Corneal Epitheliopathy Epithelial Defect Epiphora Lid Inflammation Ectropion
Bahrami 2013 [19] 89 6% 1% 10% 62% 1%
Gichuhi 2016 [46] 47 0% 0% 49% 14% 0%
Joag 2016 [47] 44 0% 0% 10% 2% 0%
Midena 2000 [44] 8 100% 0% 0% 0% 0%
Parrozzani 2016 [45] 41 28% 0% 0% 8% 0%
Rudkin 2014 [27] 12 0% 8% 0% 42% 0%
Venkateswaran 2018 [48] 54 7% 0% 22% 9% 0%