Table 1.
Various plants from different plant families, which are well reported as sources of podophyllotoxin.
| S. No. | Family; Plant(s) |
Part Used | Derivative | Ref. |
|---|---|---|---|---|
| 1 |
Apiaceae;
Chaerophyllum aurium |
Extract of subaerial part | Deoxy podorhizone and deoxypodophyllotoxin | [67] |
| 2 |
Acanthaceae;
Justicia heterocarpa |
Extract of aerial part | Podophyllotoxin lignan | [68] |
| 3 |
Berberidaceae; Jeffersonia diphylla, Dysosma pleiantha, Dysosma versipellis var. tomentosa, Dysosma versipellis |
Extract of root, Culture of Callus, | Podophyllotoxin, kaempferol and quercetin, Podophyllotoxin derivatives, 4-demethylisopodophyllotoxin | [69,70,71,72,73] |
| 4 |
Burseraceae;
C. incisa B. permollis B. fagaroides B. microphylla B. konkinensis |
Resin, Stem bark, Exudate, Stem, Extract of root | Derivatives of podophyllotoxin, Deoxypodophyllotoxin, 4-demethyldeoxypodophyllotoxin | [74,75,76,77,78] |
| 5 |
Broginaceae;
L. erythrorhizon |
Extract of needle leaf | Podophyllotoxin and derivatives | [79] |
| 6 |
Cupressaceae;
J. sabina J. virginia J. conferta C. preissii J. depressa C. rhomboidea J. virginiana J. chinensis J. horizontalis J. davurica C. endlicher J. thurifera C. drummondii C. intratropica J. squamata J. chinensis C. collumelaris J. scopulorum J. lucayana J. virginiana J. silicicola J. viriginia T. occidentalis |
Extract of needle leaf, Culture of suspension, culture of callus, needle leaf aqueous suspension, extract of needle leaf, Extract of stem, Extract of wood, Aerial part, Twig and extract of needle leaf | Podophyllotoxin and derivatives, Deoxypodophyllotoxin, 5-methoxypodophyllotoxin | [79,80,81,82,83,84,85,86,87,88,89,90,91,92] |
| 7 |
Linaceae; L. perenne L. scabrellum L. thracicum spp. L. capatitum L. elegans L. austriacum L. arboreum L. hirsutum L. usitatissimum L. scabrellum L. strictum spp. L. album L. flavum L. mucronatum spp. L. persicum L. nodiflorum L. mucronatum |
Culture of hairy root, Culture of suspension, Seed extract, root extract, aerial part, Callus, Tissue culture, Aerial Tissue culture, cell culture | Podophyllotoxin, Podophyllotoxin derivatives, 5-methoxypodophyllotoxin, 6-methylpodophyllotoxin, 6-methoxypodophyllotoxin | [86,91,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107] |