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pH-responsive behaviour of the CNs: (a) Z-average diameters over time at different pH values from 3 to 6.3. The results suggest the degree of swelling is proportional to the acidity of the suspension. The swelling behaviour was also rapid, and reached equilibrium 10 min after pH adjustment. (b) The pH-responsive behaviour was further examined through pH cycling between pH 6.3 and 4. The nanoparticles were able to swell and contract accordingly based on the pH.
