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. 2021 Apr 18;11(4):597. doi: 10.3390/biom11040597

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Structural comparison between MtbRimM_CTD and RimM from T. thermophilus HB8 (TthRimM) represented in cartoon. (A–C) β3-β4 loop of MtbRimM_CTD (A), free TthRimM (B), S19-complexed TthRimM (C). (D,E) β4-β5 loop of MtbRimM_CTD (D) and free TthRimM (E). The dihedral angle ψ of F149 in (D) and L140 in (E) are identified. The length of the hydrogen bond (V154)N-H…O(V150) is also depicted in (D), where backbone oxygen or nitrogen atoms are shown as red and blue sticks, respectively. Hydrogen atoms, if applicable, are hidden. (F,G) β5 and β6 strands of MtbRimM_CTD (F) and free TthRimM (G).