Table 2.
Responders (n = 34) | Impaired (n = 11) | p-Value | |
---|---|---|---|
Age | 61.00 ± 11.00 | 66.73 ± 7.00 | 0.09 |
Sex Ratio (H/F) | 12/22 | 2/9 | 0.46 |
Body Mass Index (kg/m2) | 26.36 ± 3.60 | 27.24 ± 2.98 | 0.44 |
Previous HA injection: n (%) | 28 (82.0) | 8 (82.0) | 1 |
Previous PRP injection: n (%) | 8 (23.5) | 4 (36.4) | 0.06 |
Volume injected | 6.50 ± 1.53 | 6.36 ±1.57 | 0.40 |
Baseline KOOS score | 35.97 ± 16.42 | 47.55 ± 14.07 | 0.02 |
Pain | 47.59 ± 20.89 | 52.36 ± 16.77 | 0.54 |
Symptoms | 48.74 ± 22.51 | 60.09 ± 16.80 | 0.15 |
ADL | 48.29 ± 21.29 | 16.09 ± 14.62 | 0.27 |
Sport | 18.85 ± 20.62 | 35.50 ±14.23 | 0.01 |
QOL | 16.82 ± 14.05 | 31.90 ± 25.44 | 0.03 |
Kellgren and Lawrence scale (%) | |||
I | 17.7% | 0% | |
II | 17.7% | 18.2% | <0.0001 |
III | 64.7% | 36.4% | |
IV | 0% | 45.4% | |
MRI characteristics according ICRS classification | |||
Proportion of patient presenting: | |||
One compartment affected | 11.5% | 3.8% | 0.01 |
Two compartments affected | 49.1% | 38.5% | |
Three compartments affected | 39.3% | 57.7% | |
Proportion of patients with at least one compart-ment presenting grade IV OA: | 46.7% | 73.0% | 0.17 |
Pain at the injection (VAS) | 27.88 ± 27.36 | 32.73 ± 24.12 | 0.55 |
HA: hyaluronic acid, PRP: Platelet-rich plasma, ADL: activities of daily living, QOL: quality of life.