Table 5.
Stratified analysis
| No. of cases | Never hormone use | Ever hormone usea | P-interaction | |
|---|---|---|---|---|
| Age ≤70 yr | 3,454 | Reference | 1.29 (1.19–1.41) | 0.36 |
| Age >70 yr | 1,971 | Reference | 1.37 (1.22–1.54) | |
| Ever smoker | 3,129 | Reference | 1.25 (1.14–1.37) | 0.04 |
| Never smoker | 2,267 | Reference | 1.42 (1.27–1.58) | |
| BMI <25 | 2,109 | Reference | 1.37 (1.22–1.54) | 0.36 |
| BMI ≥25 | 3,315 | Reference | 1.27 (1.17–1.39) | |
| Natural menopause | 2,860 | Reference | 1.36 (1.25–1.48) | 0.33 |
| Surgery/radiation | 2,565 | Reference | 1.24 (1.10–1.40) | |
| Ever OC use | 2,526 | Reference | 1.40 (1.26–1.55) | 0.16 |
| Never OC use | 2,899 | Reference | 1.26 (1.15–1.38) | |
| Fiber intake, <18 g/d | 2,478 | Reference | 1.28 (1.17–1.41) | 0.11 |
| Fiber intake, >18 g/d | 2,947 | Reference | 1.38 (1.24–1.53) |
BMI, body mass index; OC, oral contraceptive.
a
HR (95% confidence interval) for age, vigorous activity, alcohol intake, smoking, aspirin use, other nonsteroidal anti-inflammatory drug use, BMI and calorie intake, age at menarche, parity, age at menopause, time since menopause, type of menopause, past use of OCs, dietary intake of fiber and red meat, and Alternative Healthy Eating Index score. The strata variable is omitted from the multivariable model.