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. 2021 Apr 19;11(4):726. doi: 10.3390/diagnostics11040726

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Distant metastasis-free survival (DMFS) analysis of L-antigen 1 (LAGE1) expression of clinical breast cancer cases. Kaplan-Meier plots, which are based on LAGE1 mRNA expression levels, displayed the DMFS prognosis of breast cancer patients. (A) Overall survival, (B) Luminal A subtype, (C) Luminal B subtype, (D) Basal subtype, (E) HER2⁺ subtype, (F) HER2⁻ subtype, (G) PR⁺ subtype, (H) PR⁻ subtype, (I) ER⁺ subtype, (J) ER⁻ subtype, (K) survival analysis for chemotherapy-treated patients and (L) chemotherapy untreated patients.An auto-cutoff was applied in this analysis to divide patients into two groups based on the best cutoff value of LAGE1 mRNA. Higher and lower expression levels of LAGE1 mRNA than the cutoff value are respectively shown in red and black. Significant correlations are shown between highly expressed LAGE1 and poor survival outcomes of breast cancer patients. The red titles of survival curves represent the significant p < 0.05, while the black titles were considered not statistically significant).