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. 2021 Apr 19;11(4):726. doi: 10.3390/diagnostics11040726

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Survival analysis of LAGE2A expression over clinical breast cancer patients. Kaplan-Meier plots were used to indicate the distant metastasis-free survival (DMFS) prediction of breast cancer patients based on LAGE2A mRNA expression. (A) Overall survival, (B) Luminal A subtype, (C) Luminal B subtype, (D) Basal subtype, (E) HER2⁺ subtype, (F) HER2⁻ subtype, (G) PR⁺ subtype, (H) PR⁻ subtype, (I) ER⁺ subtype, (J) ER⁻ subtype, (K) survival analysis for chemotherapy-treated patients and (L) chemotherapy untreated patients. An auto-cutoff was applied in this analysis to divide patients into two groups based on the best cutoff value of LAGE2A mRNA. Higher and lower expression of LAGE2A mRNA than the cutoff value are respectively shown in red and black. Significant correlations (p < 0.05) are shown between highly expressed LAGE2A and poor survival outcomes of breast cancer patients. Similarly, significant curves were presented in red titles, and black titles showed non-significant results.