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. 2021 Apr 19;11(4):726. doi: 10.3390/diagnostics11040726

Figure 8.

Figure 8

L-Antigen 2B (LAGE2B) is particularly overexpressed in breast cancer patients. (A) In order to discover prospective gene networks and pathways impacted by the chosen genes, we exported LAGE2B co-expressed genes from TCGA and METABRIC breast cancer datasets to the MetaCore pathway analytical tool. (B) The MetaCore pathway analysis of “biology processes” indicated that “immune response_IFN-alpha/beta signaling via PI3K and NF-κB”-related pathways were correlated with breast cancer development.