ACC	acetyl-CoA carboxylase
AhR	aryl hydrocarbon receptor
ALT	alanine aminotransferase
AOP	adverse outcome pathways
AST	aspartate Aminotransferase
ATP	adenosine triphosphate
Bcl2	b-cell lymphoma 2
BFR	brominated flame retardants
cAMP	cyclic adenosine monophosphate
CAR	chimeric antigen receptor
CCR5	c-c chemokine receptor type 5
CD36	cluster of differentiation 36
cGAMP	cyclic guanosine monophosphate-adenosine monophosphate
cGAS	cyclic guanosine monophosphate-adenosine monophosphate synthase
ChREBP	carbohydrate-responsive element-binding protein
CYP450	cytochrome P450
DAMPs	damage-associated molecular patterns
DGAT	diacylglycerol acyltransferase
ERK	extracellular-signal-regulated kinase
FAS	fatty acid synthase
FR	flame retardants
FXR	farnesoid X receptor
GLUT4	glucose transporter type 4
HCC	hepatocellular carcinoma
HMGB1	high mobility group box protein 1
HFD	high-fat diet
IFN	interferon
IFNGR	interferon-gamma receptor
IL	interleukin
IRF	interferon regulatory factor
IRS	insulin receptor substrate
ISGs	interferon-stimulated genes
ISRE	interferon-stimulated response elements
JAK1	Janus kinase 1
JNK	c-jun N-terminal protein kinase
LXR	liver X receptor
MAPK	mitogen-activated protein kinase
MCP	monocyte chemoattractant protein
MDC	metabolic disrupting chemicals
MIE	molecular initiating events
mtDNA	mitochondrial DNA
mTOR	mammalian target of rapamycin
NAFLD	nonalcoholic fatty liver disease
NASH	nonalcoholic steatohepatitis
NLRs	nucleotide-binding oligomerization domain-like receptors
NR	nuclear receptor
NXR	nuclear xenobiotic receptors
OPFRs	organophosphorus flame retardants
PAMP	pathogen-associated molecular patterns
PBDEs	polybrominated diphenyl ethers
PBMC	peripheral blood mononuclear cells
PI3K	phosphoinositide 3-kinase
PPAR	peroxisome proliferator-activated receptor
PRR	pattern recognition receptors
PXR	pregnane X receptor
RAGE	receptor for advanced glycation end products
ROS	reactive oxygen species
RXR	retinoid X receptor
SCD-1	stearoyl-CoA desaturase-1
SOCS	suppressor of cytokine signaling
SREBP	sterol regulatory element-binding protein
STAT	signal transducer and activator of transcription
STING	stimulator of interferon genes
T2D	type 2 diabetes mellitus
TAFLD	toxicant-associated fatty liver disease
TASH	toxicant-associated steatohepatitis
TGFβ	transforming growth factor-beta
TH	thyroid hormone
TLR	Toll-like receptor
TNF	tumor necrosis factor
TYK2	tyrosine kinase 2
VLDL	very-low-density lipoprotein