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. 2021 Apr 20;13(4):713. doi: 10.3390/v13040713

Figure 5.

Figure 5

Reproducibility of pseudotype SARS-CoV-2 virus neutralisation test (pVNT) and comparison to the SARS-CoV-2 virus neutralisation test (VNT). (A) Titres from the pVNT, conducted and analysed independently at two separate institutions, from a subset of sera from individuals that had symptomatic disease consistent with SARS-CoV-2 infection during the pandemic tested by VNT and ELISA in Figure 1. (B) pVNT titres from samples taken for up to 93 or 97 days post symptom onset from three COVID-19 symptomatic individuals tested in Figure 2. (C–E) Comparison between SARS-CoV-2 VNT and pVNT on a subset serum samples from a group of PCR positive human patient sera from the University Hospitals Southampton NHS Foundation Trust. Comparison of pVNT titres on the serum panel using independently generated pseudotyped viruses from three separate locations; (C) APHA (institution 1), (D) University of Kent (Institution 2) and (E) University of Sussex (institution 3).