Fig. 4.

Dynamics and functions of genes with changing expression patterns over time. a Temporal dynamics of DE transcription factors show that many transcription factors reach their maximal expression 1–2 h after Imd stimulation. b Heatmap showing most up- and down-regulated pathways (orange and purple respectively) through the first 48 h post-injections (absolute pathway score > 2.5 and P-value < 0.05 in at least one time point). c-d Gene Set Analysis identifies up- and down-regulated pathways. Selected significantly down-regulated metabolic pathways with corresponding gene memberships