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Critical steps of SARS-CoV-2 infection involving lipid homeostasis. Some key steps of SARS-CoV-2 infection, ranging from the virus life cycle to the inflammatory response, can be affected by targeting the mevalonate pathway, making it a potential therapeutic target to counteract COVID-19.
S, Spike protein; M, Membrane proteins; E, Envelope protein; N, Nucleocapsid protein; ER, Endoplasmic reticulum; DMVs, Double Membrane vesicles; CVDs, Cardiovascular diseases.
