Table 2.
Summary of disease burden, impact and cost-effectiveness ratios, with and without intervention (2030–2039), baseline scenario
| Country group by | N | Disease burden without intervention | Burden averted and ICER with RSV maternal vaccine | Burden averted and ICER with RSV mAb | |||||||||||
| Non-severe cases | Severe cases | Hospitalisations | Deaths | Non-severe cases | Severe cases | Hospitalisations | Deaths | ICER per DALY averted | Non-severe cases | Severe cases | Hospitalisations | Deaths | ICER per DALY averted | ||
| Gavi status | |||||||||||||||
| Gavi | 73 | 31 288 677 | 10 683 106 | 8 031 827 | 352 990 | 2 159 630 | 1 730 164 | 1 333 545 | 83 024 | 1073 | 13 866 799 | 4 742 022 | 3 565 171 | 182 800 | 315 |
| Non-Gavi | 58 | 10 657 947 | 4 599 391 | 3 457 938 | 151 973 | 819 749 | 907 088 | 699 149 | 43 528 | 1681 | 5 610 598 | 2 441 921 | 1 835 898 | 94 133 | 577 |
| World Bank income group | |||||||||||||||
| LIC | 34 | 10 823 869 | 3 562 172 | 2 678 130 | 117 701 | 760 348 | 577 452 | 445 078 | 27 710 | 949 | 4 774 083 | 1 573 199 | 1 182 771 | 60 645 | 257 |
| LMIC | 46 | 22 502 889 | 7 872 029 | 5 918 389 | 260 107 | 1 559 549 | 1 292 990 | 996 588 | 62 046 | 1311 | 10 083 892 | 3 536 660 | 2 658 950 | 136 334 | 428 |
| UMIC | 51 | 8 619 867 | 3 848 296 | 2 893 246 | 127 155 | 659 482 | 766 809 | 591 027 | 36 796 | 1631 | 4 619 422 | 2 074 084 | 1 559 348 | 79 954 | 551 |
| WHO geographic region | |||||||||||||||
| EAP | 20 | 5 313 235 | 3 097 972 | 2 329 133 | 102 363 | 314 036 | 582 849 | 449 238 | 27 969 | 1411 | 2 570 416 | 1 558 912 | 1 172 029 | 60 094 | 479 |
| ECA | 20 | 2 609 512 | 633 363 | 476 178 | 20 928 | 244 307 | 125 417 | 96 666 | 6018 | 1425 | 1 398 536 | 337 329 | 253 612 | 13 004 | 437 |
| LAC | 23 | 2 583 464 | 1 024 279 | 770 079 | 33 844 | 209 296 | 204 837 | 157 881 | 9829 | 1507 | 1 349 631 | 536 105 | 403 057 | 20 666 | 507 |
| MENA | 13 | 2 907 732 | 1 058 521 | 795 823 | 34 976 | 222 211 | 192 789 | 148 594 | 9251 | 1566 | 1 468 837 | 535 629 | 402 699 | 20 648 | 532 |
| SA | 8 | 12 207 891 | 4 018 853 | 3 021 474 | 132 791 | 842 810 | 643 028 | 495 622 | 30 857 | 1138 | 5 628 427 | 1 857 416 | 1 396 452 | 71 601 | 342 |
| SSA | 47 | 16 324 790 | 5 449 509 | 4 097 078 | 180 062 | 1 146 719 | 888 332 | 684 693 | 42 628 | 1169 | 7 061 551 | 2 358 554 | 1 773 220 | 90 920 | 359 |
| Total | 131 | 41 946 624 | 15 282 497 | 11 489 765 | 504 963 | 2 979 379 | 2 637 252 | 2 032 693 | 126 552 | 1342 | 19 477 397 | 7 183 943 | 5 401 069 | 276 933 | 431 |
DALY, disability-adjusted life year; EAP, East Asia & Pacific; ECA, Europe & Central Asia; ICER, incremental cost-effectiveness ratio; LAC, Latin America & Caribbean; LIC, low-income country; LMIC, low-income and middle-income country; MENA, Middle East & North Africa; RSV, respiratory syncytial virus; SA, South Asia; SSA, Sub-Saharan Africa; UMIC, upper-middle-income country.