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. 2021 Apr 21:1–12. doi: 10.1080/13543776.2021.1884224

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 9. — Structural comparison of diketoacid group containing compounds. A well-known HIV-1 integrase inhibitors dolutegravir, which has a diketoacid group is included as a reference compound. The other two structures represent patented inhibitors of SARS-CoV nsp13 inhibitors. 1-ADK refers to a patented compound 1 containing ADK group (KR20110006083A; 2011)