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. 2021 Apr 12;11:641195. doi: 10.3389/fonc.2021.641195

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Copyright © 2021 Hu, Shen, Han, Mao, Mao, Li, Li, Guo and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Images in a 63-year-old man with chronic hepatitis B virus infection and pathological confirmed intrahepatic cholangiocarcinoma lesion, which was correctly classified as LR-M both on CEUS and gadopentetate-enhanced MRI. T1-weighted image shows a 58-mm nodule in hepatic segment II/III/IV with rim arterial phase hyperenhancement (arrow) in (A) arterial phase followed by delayed central enhancement (arrow) in (B) portal phase. Contrast-enhanced US image shows a 68-mm nodule with rim arterial phase hyper-enhancement (arrow) in (C) arterial phase (timer, 00:22) followed by marked washout (arrow) visible in (D) portal phase (timer, 01:49).