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. 2021 Apr 12;11:641195. doi: 10.3389/fonc.2021.641195

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Copyright © 2021 Hu, Shen, Han, Mao, Mao, Li, Li, Guo and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Images in a 54-year-old man with chronic hepatitis B virus infection and pathological confirmed combined hepatocellular cholangiocarcinoma, which was correctly classified as LR-M on CEUS but mistaken as LR-5 on gadopentetate-enhanced MRI. T1-weighted image shows a 53-mm nodule in hepatic segment VI with arterial phase hyperenhancementand (arrow) in (A) arterial phase followed by enhancing capsule (arrow) and non-rim washout in (B) delayed phase. Contrast-enhanced US image shows a 64-mm nodule with heterogeneous hyperenhancement (not rim or peripheral discontinued globular enhancement) (arrow) in (C) arterial phase (timer, 00:19) followed by early washout (arrow) in (D) portal phase (timer, 00:51) and mild washout in delayed phase.