Table 4.

The nominal maximum dose D_1% to various serial organs and mean dose D_mean to cochlea from the competing treatment plans and their worst case increase D_1% and D_mean. Units are Gy RBE for proton and Gy for photon plans

Structure	Indices	Techniques
		SFO	MFO	HB-MFO	IMRT	RB-IMRT
Brain stem	NM-D1%	53.64±6.74	53.68±2.84	50.38±2.32	52.71±3.08	51.61±2.08
	WI-D1%	63.11±3.64	66.97±2.82	63.55±2.33	67.78±3.14	64.32±2.14
Chiasm	NM-D1%	52.84±1.72	52.81±1.38	50.09±1.81	50.10±3.65	50.10±1.80
	WI-D1%	63.81±3.38	66.20±2.92	63.62±2.40	70.78±4.32	64.12±3.10
Spinal cord	NM-D1%	46.65±3.00	47.02±3.70	44.55±2.30	45.52±3.70	45.10±3.10
	WI-D1%	59.20±2.46	62.87±1.32	58.69±2.30	65.14±2.52	60.10±1.84
RT-optic nerve	NM-D1%	58.14±8.21	54.92±8.50	52.35±2.32	53.09±6.31	52.01±3.30
	WI-D1%	66.59±3.34	67.17±5.94	65.60±2.04	69.53±1.62	66.32±3.52
LT-optic nerve	NM-D1%	51.22±2.18	51.40±3.70	49.50±1.10	49.15±2.90	50.71±3.10
	WI-D1%	63.48±5.20	64.83±1.69	63.20±1.76	69.32±3.03	64.10±1.89
RT-temporal lob	NM-D1%	62.88±4.71	61.67±3.43	57.26±3.53	62.56±3.85	61.54±2.81
	WI-D1%	67.54±2.80	68.77±3.14	65.76±3.58	70.06±4.18	67.14±2.90
LT-temporal lob	NM-D1%	6349±3.93	62.53±5.86	57.39±4.44	63.93±4.40	62.13±3.30
	WI-D1%	68.03±2.72	68.84±4.26	65.60±3.74	71.47±4.39	66.60±3.39
RT-cochlea	NM-Dmean	36.63±8.19	34.47±7.25	27.45±3.08	37.27±8.34	33.12±4.89
	WI-Dmean	39.66±10.35	41.76±11.45	35.06±11.12	44.69±8.24	40.89±5.32
LT cochlea	NM-Dmean	31.77±17.3	30.97±17.40	28.84±18.8	34.74±15.10	32.12±14.35
	WI-Dmean	42.16±5.23	47.74±8.39	41.40±4.43	48.68±5.20	45.32±6.20

SFO: Single field uniform optimization, MFO: Multi field optimization, HB-MFO: Hybrid-multi field optimization, IMRT: Intensity modulated radiotherapy, RB-IMRT: Robustly optimized-intensity modulated radiotherapy, NM-D: Nominal maximum dose, WI-D: Worst case increase dose