Figure 1.

Pancreatic ductal adenocarcinoma and its desmoplastic, hypovascular tumour stroma. This fibrotic capsule contains a high concentration of extracellular matrix (ECM) components such as collagen, hyaluronic acid, laminins, and fibronectin partially produced by a dense population of cancer-associated fibroblasts. This schematic focuses on ECM components within the 3D tumouroid model. Created using Servier Medical Art according to the Creative Commons Attribution 3.0 Unported License guidelines 3.0 (https://creativecommons.org/licenses/by/3.0/, accessed on 9 February 2021).