Table 3.
Minimum inhibitory concentrations (MIC) of the pure compounds (1–16) isolated from E. nigrum M13 and A. alternata 13A against bacterial and fungal pathogens.
| Compound | Minimum Inhibitory Concentration (MIC, µg/mL) * | ||||||
|---|---|---|---|---|---|---|---|
| S. aureus | B. subtilis | E. coli | K. pneumonia | P. vulgaris | P. aeruginosa | C. albicans | |
| 1 | 2.5 | 2.5 | 10 | 20 | 10 | 30 | 30 |
| 2 | 50 | 40 | - | - | - | - | - |
| 3 | 20 | 20 | - | - | - | - | - |
| 4 | 10 | 10 | 30 | 30 | 30 | - | - |
| 5 | 10 | 10 | 30 | 30 | 30 | - | - |
| 6 | 40 | 40 | - | - | - | - | 40 |
| 7 | 5 | 5 | 20 | - | - | 10 | 20 |
| 8 | 30 | 40 | 30 | 40 | 40 | - | 50 |
| 9 | 10 | 10 | - | - | - | - | - |
| 10 | - | - | - | - | - | - | - |
| 11 | 20 | 20 | - | - | - | 30 | 50 |
| 12 | 20 | 30 | - | - | - | 40 | 50 |
| 13 | 30 | 30 | - | - | - | - | 40 |
| 14 | 30 | 30 | - | - | - | - | 40 |
| 15 | 30 | 20 | - | - | - | - | 40 |
| 16 | 30 | 20 | - | - | - | - | 30 |
| Cip | 0.62 | 0.31 | 1.25 | 1.25 | 1.25 | 2.5 | - |
| Nys | - | - | - | - | - | - | 5 |
* The average of two independent replicates, positive controls: Cip: Ciprofloxacin; Nys: Nystatin; -: not detected.