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. 2021 Apr 12;9:647522. doi: 10.3389/fcell.2021.647522

TABLE 3.

Studies of embryo development after silencing of ADAMTS1.

si-Ctrl (n = 48) si-ADAMTS1 (n = 48) p-value
Development time to morula stage (h) 68.21 ± 2.66 77.05 ± 3.09 0.037
Good-quality embryo rate (%) 76.3 65.8 0.312
Morula formation rate (%) 47.4 47.4 1.000
Blastocyst formation rate (%) 28.9 31.6 0.803
Good-quality blastocyst rate (%) 27.3 25.0 0.901

The development time to morula stage is calculated from the time of siRNA injection. Good-quality embryo rate (%) = (number of D3 good-quality embryos/number of cleaved embryos) × 100; Morula formation rate (%) = (number of morulae/number of embryos cultured) × 100; Blastocyst formation rate (%) = (number of blastocysts/number of embryos cultured) × 100; Good-quality blastocyst rate (%) = (number of good-quality blastocysts/number of blastocysts) × 100. p < 0.05 was considered statistically significant.