Table 2.
Burden and Prevalence of Non-AIDS Comorbidities in Women Stratified by Human Immunodeficiency Virus Serostatus and Age Group
| NACM | HIV Positive | HIV Negative | HIV × Age Interaction, Pb | ||||||
|---|---|---|---|---|---|---|---|---|---|
| <40 Years (n = 315) | 40–49 Years (n = 711) | 50–59 Years (n = 936) | ≥60 Yearsa (n = 347) | <40 Years (n = 205) | 40–49 Years (n = 285) | 50–59 Years (n = 305) | ≥60 Yearsa (n = 128) | ||
| Hypertension | 99 (31) | 413 (58) | 698 (75) | 322 (93) | 77 (38) | 146 (51) | 246 (81) | 119 (93) | .0169 |
| Psychiatric illness | 122 (39) | 385 (54) | 574 (61) | 231 (67) | 65 (32) | 120 (42) | 187 (61) | 73 (57) | .0816 |
| Lung disease | 91 (29) | 249 (35) | 442 (47) | 172 (50) | 68 (33) | 103 (36) | 157 (51) | 64 (50) | .8503 |
| Liver disease | 76 (24) | 239 (34) | 482 (52) | 233 (67) | 21 (10) | 63 (22) | 94 (31) | 59 (46) | .4073 |
| Dyslipidemia | 54 (17) | 244 (34) | 413 (44) | 215 (62) | 32 (16) | 64 (22) | 150 (49) | 73 (57) | .0023 |
| Bone disease | 41 (13) | 208 (29) | 447 (48) | 233 (67) | 30 (15) | 72 (25) | 126 (41) | 73 (57) | .3940 |
| Diabetes mellitus, type 2 | 23 (7) | 113 (16) | 244 (26) | 122 (35) | 17 (8) | 48 (17) | 105 (34) | 55 (43) | .5365 |
| Cardiovascular disease | 15 (5) | 89 (13) | 210 (22) | 124 (36) | 12 (6) | 37 (13) | 84 (28) | 45 (35) | .6543 |
| Chronic kidney disease | 7 (2) | 37 (5) | 160 (17) | 145 (42) | 0 (0) | 2 (<1) | 26 (9) | 33 (26) | .3004 |
| Cancer, non-AIDS | 8 (3) | 64 (9) | 119 (13) | 60 (17) | 7 (3) | 11 (4) | 32 (10) | 18 (14) | .1914 |
| Mean (SD) NACM burden | 1.7 (1.4) | 2.9 (1.8) | 4.0 (2.0) | 5.4 (1.9) | 1.6 (1.4) | 2.3 (1.8) | 4.0 (2.0) | 4.8 (2.0) | .0206 |
Data are presented as n (%) unless otherwise indicated.
Abbreviations: HIV, human immunodeficiency virus; NACM, non-AIDS comorbidity.
aWilcoxon test performed for linear trend across (ordinal) age groups for categorical variables (ie, prevalence of each comorbidity) and unadjusted linear regression performed for continuous variables (ie, NACM burden) stratified by HIV serostatus: all P values were < .0001 for each prevalent comorbidity and NACM burden within each strata of HIV serostatus.
bPartially adjusted logistic regression performed for the prevalence of each comorbidity and partially adjusted linear regression for NACM burden with HIV serostatus, categorized age, and HIV × age interaction terms in the model.