Table 3.
Multivariable Analysis of Risk Factors at End of Observation Associated With the Burden of Non-AIDS Comorbidities in Women Living With or at Risk for Human Immunodeficiency Virus Infection
| Risk Factor | Estimated Mean Number of NACMs (95% CI) | B (±SE) | P a |
|---|---|---|---|
| HIV serostatusb | <.0001 | ||
| Positive | 3.46 (3.30, 3.63) | 0.40 (±0.08) | |
| Negative | 3.07 (2.89, 3.24) | Ref | |
| Age groupb | <.0001 | ||
| ≥60 y | 4.49 (4.25, 4.73) | 2.40 (±0.14) | |
| 50–59 y | 3.77 (3.60, 3.94) | 1.68 (±0.11) | |
| 40–49 y | 2.70 (2.52, 2.88) | 0.61 (±0.10) | |
| <40 y | 2.09 (1.88, 2.30) | Ref | |
| Race | <.0001 | ||
| Non-Hispanic AA | 3.09 (2.95, 3.22) | −0.40 (±0.11) | |
| Hispanic | 3.00 (2.81, 3.18) | −0.50 (±0.12) | |
| Other non- Hispanic | 3.48 (3.13, 3.83) | −0.02 (±0.20) | |
| White | 3.49 (3.27, 3.72) | Ref | |
| Body mass index | <.0001 | ||
| ≥30 kg/m2 | 3.51 (3.34, 3.67) | 0.48 (±0.06) | |
| <30 kg/m2 | 3.02 (2.86, 3.18) | Ref | |
| Education | .3517 | ||
| ≤High school | 3.23 (3.07, 3.39) | −0.07 (±0.07) | |
| >High school | 3.30 (3.12, 3.47) | Ref | |
| Income | <.0001 | ||
| <$12 000 | 3.63 (3.46, 3.79) | 0.84 (±0.08) | |
| $12 001– $24 000 | 3.38 (3.19, 3.57) | 0.59 (±0.09) | |
| >$24 000 | 2.79 (2.60, 2.97) | Ref | |
| Marital status | .1108 | ||
| Had a partner | 3.35 (3.17, 3.53) | 0.09 (±0.09) | |
| Never partner/other | 3.18 (3.01, 3.36) | −0.07 (±0.08) | |
| Married/ partner | 3.26 (3.08, 3.44) | Ref | |
| Own residence | .2937 | ||
| No | 3.22 (3.02, 3.41) | −0.09 (±0.09) | |
| Yes | 3.31 (3.16, 3.46) | Ref | |
| Cigarette use | <.0001 | ||
| Current | 3.61 (3.45, 3.78) | 0.77 (±0.08) | |
| Former | 3.33 (3.15, 3.51) | 0.48 (±0.08) | |
| Never | 2.85 (2.66, 3.04) | Ref | |
| Current alcohol use | .0467 | ||
| >7 drinks/ wk | 3.15 (2.91, 3.39) | −0.24 (±0.12) | |
| 1–7 drinks/ wk | 3.26 (3.09, 3.42) | −0.13 (±0.07) | |
| None | 3.39 (3.22, 3.56) | Ref | |
| Crack/cocaine use | <.0001 | ||
| Current | 3.30 (3.04, 3.56) | 0.24 (±0.13) | |
| Former | 3.43 (3.25, 3.62) | 0.38 (±0.08) | |
| Never | 3.06 (2.91, 3.21) | Ref |
Abbreviations: AA, African American; HIV, human immunodeficiency virus; NACM, non-AIDS comorbidity; Ref, reference; WIHS, Women’s Interagency HIV Study.
aAdjusted linear regression with all covariates listed included in the model plus WIHS enrollment wave; assessing HIV × age interaction: P = .0978.
bAdjusted for HIV serostatus × age interaction.