Table 2.
Stress vs. Baseline | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PTSD symptom group vs. TC |
TC vs. PTSD symptom group |
|||||||||||||
Region | X | Y | Z | Z-score | Cluster size | p | Region | X | Y | Z | Z-score | Cluster size | p | |
R Hippocampus | R Cerebellum | 16 | −58 | −16 | 4.11 | 28 | < .001 | L Middle Frontal Gyrus | −54 | 18 | 44 | 3.99 | 20 | .002 |
L Hippocampus | L Inferior Frontal Gyrus (pars opercularis) | −58 | 16 | 34 | 3.85 | 31 | < .001 | |||||||
R Middle Frontal Gyrus | 54 | 28 | 38 | 3.73 | 18 | .004 | ||||||||
R Amygdala | ||||||||||||||
L Amygdala | ||||||||||||||
mPFC |
|
|
|
|
|
|
|
L Inferior Frontal Gyrus (pars opercularis) |
−58 |
16 |
34 |
3.92 |
42 |
< .001 |
Recovery vs. Baseline | ||||||||||||||
PTSD symptom group vs. TC |
TC vs. PTSD symptom group |
|||||||||||||
|
Region |
X |
Y |
Z |
Z-score |
Cluster size |
p |
Region |
X |
Y |
Z |
Z-score |
Cluster size |
p |
R Hippocampus | L Inferior Frontal Gyrus (pars opercularis) | −58 | 16 | 34 | 3.80 | 22 | .001 | |||||||
L Hippocampus | L Inferior Frontal Gyrus (pars opercularis) | −58 | 16 | 34 | 3.85 | 37 | < .001 | |||||||
R Middle Frontal Gyrus | 54 | 28 | 38 | 3.68 | 24 | < .001 | ||||||||
R Amygdala | ||||||||||||||
L Amygdala | ||||||||||||||
mPFC | L Inferior Frontal Gyrus (pars opercularis) | −58 | 16 | 34 | 3.75 | 28 | < .001 |
Significant results after correcting for multiple testing by FDR correction (α = 0.01) according to Benjamini and Hochberg (1995). Regions were identified using the Harvard-Oxford Cortical and Subcortical Structural Atlases or if probability of the labels was low (<15%) using the MNI Structural Atlas. PTSD symptom group n = 17, TC n = 22.