Table 4.

Association between examined factors and medication non-adherence at 1 year follow-up^*

Factors	ACEI/ARB	Antiplatelet	Beta-blocker	Statin
Patient		Young age (<55) ↑29 or NS21	Increasing age ↑34	Increasing age ↑34
		Sex: male (NS)21	Sex: male ↑34	Sex: male (NS)34
	Non-white (vs. White) ↑23		Non-white (vs. White) ↑23	Non-white (vs. White) ↑23
	Asian (vs. Non-Asian) ↑25	US geographic region: West ↓21
Socioeconomic			Low income (NS)34	Low income (NS)34
Health System		Reimbursement type (NS)21
			Specialty of attending physician (NS)34	Specialty of attending physician (NS)34
Therapy		Prior use of clopidogrel ↑29	Prior use of beta-blocker ↓34	Prior use of statin ↓34
		Prior use of beta-blockers, statins, ACE inhibitors ↓29
		Medication received during baseline: Statin ↓21	Concomitant statin ↓34	Concomitant beta-blocker ↓34
		Medication received during baseline: anticoagulant ↑21	Concomitant ACE inhibitors ↓34	Concomitant ACE inhibitors ↓34
		Prior PCI procedure ↑21	Post-MI revascularization ↑34	Post-MI revascularization ↓34
		PCI without stenting during hospitalization ↑29
Condition		Diabetes ↑29	Diabetes (NS)34	Diabetes (NS)34
		Atrial Fibrillation (NS)29	Cardiac dysrhythmia ↑34	Cardiac dysrhythmia (NS)34
		History of bleeding ↑21
		Depression ↑21 or NS29	Post-MI: psychiatric illnesses ↑34	Post-MI: psychiatric illnesses ↑34
		COPD ↑29	Post-MI: Respiratory illness ↑34	Post-MI Respiratory illness (NS)34
			Post MI: Cancer ↑34	Post MI: Cancer (NS)34
		Any prior hospitalization ↑29	Increasing numbers of recurrent admissions post discharge↑34	Increasing numbers of recurrent admissions post discharge↑34
		Renal disease (NS)29	Acute renal failure (NS)34	Acute renal failure (NS)34
			Chronic renal failure (NS)34	Chronic renal failure (NS)34
		Hypertension (NS)29	Other conditions† (NS)34	Other conditions† (NS)34
		Charlson/Deyo Comorbidity Index (2+ vs. ≤1) (NS)21
		UA/NSTEMI (vs. STEMI/other) (NS)29

^*↑: significantly increased; ↓ significantly decreased; NS: not significant

^†Other conditions include: shock, pulmonary edema, congestive heart failure, cerebrovascular disease, cancer, post-MI: ischemic heart disease, post MI: endocrine illness, post MI: apoplexia (MI=myocardial infraction)