Table 3.
Stratified Analyses of the Association Between Anemia and Frailty Status According to Baseline Characteristics
| Characteristics | Frail Anemia/Total (%) | Non-Frail Anemia/Total (%) | OR (95% CI) | P value for Interaction |
|---|---|---|---|---|
| Age | 0.173 | |||
| <70 | 23/65 (35.38) | 28/303 (9.24) | 5.38 (2.84, 10.20) | |
| ≥70 | 45/104 (43.27) | 30/147 (20.41) | 2.97 (1.70, 5.20) | |
| Sex | 0.029 | |||
| Male | 39/89 (43.82) | 46/245 (18.78) | 3.37 (1.99, 5.72) | |
| Female | 29/80 (36.25) | 12/205 (5.85) | 9.15 (4.36, 19.17) | |
| BMI | 0.150 | |||
| <18.5 | 6/11 (54.55) | 7/13 (53.85) | 1.03 (0.21, 5.15) | |
| 18.5~23.9 | 32/77 (41.56) | 29/199 (14.57) | 4.17 (2.29, 7.60) | |
| >23.9 | 30/81 (37.04) | 22/238 (9.24) | 5.78 (3.08, 10.83) | |
| Current smoker | 0.736 | |||
| No | 51/134 (38.06) | 39/348 (11.21) | 4.87 (3.01, 7.89) | |
| Yes | 17/35 (48.57) | 19/102 (18.63) | 4.13 (1.80, 9.46) | |
| Current drinker | 0.120 | |||
| No | 54/144 (37.50) | 48/365 (13.15) | 3.96 (2.52, 6.24) | |
| Yes | 14/25 (56.00) | 10/85 (11.76) | 9.55 (3.41, 26.71) | |
| CCI | 0.889 | |||
| <3 | 31/93 (33.33) | 34/315 (10.79) | 4.13 (2.36, 7.23) | |
| ≥3 | 37/76 (48.68) | 24/135 (17.78) | 4.39 (2.34, 8.24) | |
| ADL | 0.329 | |||
| <100 | 56/123 (45.53) | 23/143 (16.08) | 4.36 (2.47, 7.71) | |
| 100 | 12/56 (26.09) | 35/307 (11.40) | 2.74 (1.30, 5.79) | |
| NRS 2002 | 0.443 | |||
| <3 | 53/142 (37.32) | 51/428 (11.92) | 4.40 (2.81, 6.89) | |
| ≥3 | 15/27 (55.56) | 7/22 (31.82) | 2.68 (0.83, 8.68) |
Note: The P value for interaction represents the likelihood of interaction between the variable and the hemoglobin concentrations.
Abbreviations: BMI, body mass index; CCI, Charlson Comorbidity Index; ADL, activities of daily living; NRS 2002, nutrition risk score 2002; OR, odds ratio; CI, confidence interval.