Table 2. Chemical characteristics of the best performing classes with PharmaNet.
Target | Characteristic |
---|---|
CXCR4 | At least one dihydroimidazole group |
FPPS | One or two phosphonic acid groups |
KITHH | One secondary amide |
SAHH | One Amino-purine |
PUR2 | Two carboxyl groups at the end of the sequence |
FABP4 | One caboxilyc acid group |
HMDH | At least one carbonyl group or one C-C-O sequence |
HS90A | One benzothiazole group |
COMT | At least one benzene group |