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. 2021 Apr 26;16(4):e0241728. doi: 10.1371/journal.pone.0241728

Table 2. Chemical characteristics of the best performing classes with PharmaNet.

Target Characteristic
CXCR4 At least one dihydroimidazole group
FPPS One or two phosphonic acid groups
KITHH One secondary amide
SAHH One Amino-purine
PUR2 Two carboxyl groups at the end of the sequence
FABP4 One caboxilyc acid group
HMDH At least one carbonyl group or one C-C-O sequence
HS90A One benzothiazole group
COMT At least one benzene group