Table 6. Group differences in ΔT1 metrics.
| NEL T1 metric |
EDSS | MS type | Treatment | |||
|---|---|---|---|---|---|---|
| ≤ Median Score | > Median Score | PMS | RRMS | No | Yes | |
| mean ΔT1 | -0.120 | -0.186 * | -0.187 | -0.122 ** | -0.192 | -0.126 ** |
| (-0.304, 0.174) | (-0.238, 0.100) | (-0.238, -0.062) | (-0.304, 0.174) | (-0.304, -0.049) | (-0.231, 0.174) | |
| median ΔT1 | -0.109 | -0.168 *** | -0.177 | -0.110 *** | -0.162 | -0.122 * |
| (-0.281, 0.134) | (-0.272, 0.050) | (-0.272, -0.118) | (-0.281, 0.134) | (-0.281, -0.045) | (-0.201, 0.134) | |
| variance ΔT1 | 0.081 | 0.118 *** | 0.119 | 0.082 ** | 0.111 | 0.083 |
| (0.026, 0.297) | (0.006, 0.366) | (0.048, 0.366) | (0.006, 0.297) | (0.006, 0.366) | (0.040, 0.337) | |
| IQR ΔT1 | 0.272 | 0.382 ** | 0.357 | 0.272 * | 0.337 | 0.297 |
| (0.142, 0.439) | (0.118, 0.702) | (0.229, 0.702) | (0.118, 0.469) | (0.118, 0.702) | (0.193, 0.689) | |
| kurtosis ΔT1 | 6.425 | 5.102 ** | 5.255 | 6.205 | 5.837 | 6.023 |
| (4.459, 14.589) | (2.636, 8.803) | (3.843, 8.803) | (2.636, 14.589) | (2.636, 14.589) | (3.843, 11.825) | |
Inter-subject median (range) is shown for each metric. Significance for group difference tested by Mann-Whitney U-test shown. Statistically significances (*: P < 0.05, **: P < 0.01, ***: P < 0.001) are shown in bold.
NEL = non-enhancing lesion; MS = multiple sclerosis; RRMS = relapsing-remitting multiple sclerosis; PMS = progressive MS (primary progressive + secondary progressive multiple sclerosis); IQR = inter-quartile range