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. 2021 Apr 26;16(4):e0250642. doi: 10.1371/journal.pone.0250642

Table 4. Logistic regression miRNAs combination models for IBC diagnosis.

EV-derived miRNAs B SE 95% CI OR Percentage Accuracy in classification (PAC) Nagelkerke R2 (%) p-value
miR-222-3p and let-7a-5p panel miR-222-3p 0.811 0.27 [0.28, 1.34] 2.25 94.7% 83.8% < 0.01
let-7a-5p -1.211 0.35 [-1.89, -0.53] 0.30 < 0.001
Let-7a-5p and miR-181b-5p panel let-7a-5p -0.915 0.29 [-1.48, -0.35] 0.40 89.5% 78.1% < 0.001
miR-181b-5p 0.442 0.15 [0.15, 0.74] 1.56 < 0.001
miR-181b-5p and miRNA-222-3p panel miR-181b-5p 0.543 0.17 [0.21, 0.88] 1.72 82.5 41.2% < 0.001
miRNA-222-3p -0.061 0.17 [-0.40, 0.28] 0.94 0.724

B: Beta regression coefficient; SE: Standard Error; 95% CI: confidence interval; OR: Odds Ratio.