Table 4. Logistic regression miRNAs combination models for IBC diagnosis.
EV-derived miRNAs | B | SE | 95% CI | OR | Percentage Accuracy in classification (PAC) | Nagelkerke R2 (%) | p-value | |
---|---|---|---|---|---|---|---|---|
miR-222-3p and let-7a-5p panel | miR-222-3p | 0.811 | 0.27 | [0.28, 1.34] | 2.25 | 94.7% | 83.8% | < 0.01 |
let-7a-5p | -1.211 | 0.35 | [-1.89, -0.53] | 0.30 | < 0.001 | |||
Let-7a-5p and miR-181b-5p panel | let-7a-5p | -0.915 | 0.29 | [-1.48, -0.35] | 0.40 | 89.5% | 78.1% | < 0.001 |
miR-181b-5p | 0.442 | 0.15 | [0.15, 0.74] | 1.56 | < 0.001 | |||
miR-181b-5p and miRNA-222-3p panel | miR-181b-5p | 0.543 | 0.17 | [0.21, 0.88] | 1.72 | 82.5 | 41.2% | < 0.001 |
miRNA-222-3p | -0.061 | 0.17 | [-0.40, 0.28] | 0.94 | 0.724 |
B: Beta regression coefficient; SE: Standard Error; 95% CI: confidence interval; OR: Odds Ratio.