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. 2021 Apr 26;16(4):e0250254. doi: 10.1371/journal.pone.0250254

Table 5. Multivariate logistic regression analysis of De1-1 protein as prognostic marker for advanced disease (pT ≥ 3b).

Total pT2 or pT3a ≥ pT3b p value HR (95% CI)
Univariate Multivariate
N 181 156 25 - - -
Age 70.75±7.02 70.47±7.14 72.48±6.09 0.184 - -
PSA 9.42±9.03 8.35±6.59 16.10±16.67 0.030 0.050 1.045 (1.000–1.092)
Del-1 protein 0.147±0.114 0.134±0.099 0.227±0.161 0.009 0.015 87.833 (2.453–5060.403)
Gleason score <0.001
    6 (3+3) or 7 (3+4) 95 88 7 Ref
    7 (4+3) or 8 (4+4) 71 60 11 0.373 1.639 (0.553–4.854)
    9 or 10 15 8 7 0.011 6.273 (1.516–25.419)