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. 2021 Apr 22;14:1601–1611. doi: 10.2147/IDR.S301802

Table 5.

Analysis the Mutations of Nitroreductase in Nitrofurantoin-Resistant Isolates

		Amino Acid Substitution(s)^a
Isolates	MICs (μg/mL)	ef0404	ef0648^b
SC1218	256	N/d	69–70 insC, 478G > A
SC1245	256	126C > T, 333G > A, 339G > A, 588T > C	478G > A
SC1310	256	N/d	478G > A
SC1324	256	126C > T, 268T > C, 294G > A	N/d
SC1393	256	N/d	267C > A, 417G >A
SC1430	256	N/d	69T > A, 417G > A, 483A > G, 549C > T
SC1597	128	N/d	489T > G
SC1672	128	N/d	267C > A, 417C > A, 489T > G
SC1779	128	N/d	52C > T

Notes: ^aN/d, failed to amplify; ^bbold fonts represent missense mutations, others are nonsense mutations.