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. 2021 Apr 12;8:572471. doi: 10.3389/fchem.2020.572471

FIGURE 1.

FIGURE 1

(A) Schematic illustration of cathepsin B-responsive biodegradable theranostic nanomedicine derived from branched pHPMA. (B) Distribution of T 1 value of tumor at different time points after injection. (C) Quantitative tumor volume changes of mice obtained by MRI after being treated with saline, Taxol, and BP-PTX-Gd NPs (n = 7, *p < 0.001 vs. saline, *p < 0.001 vs. Taxol). (D) Images of the tumors harvested from the mice 21 days after the treatment. (E) The tumor weight of tumor-bearing mice after treatment (*p < 0.001 vs. saline, *p < 0.001 vs. Taxol). Reproduced with permission from Cai H. et al. (2020). Copyright 2020 Wiley-VCH Verlag GmbH & Co. KgaA.