FIGURE 4.

(A) The scheme of tumor targeting gene vectors for visual tracking of Bcl-2 siRNA transfection and anti-tumor therapy. (B) Body weight changes of the nude mice of different groups over 41 days; (C) Fluorescent confocal laser scanning microscopic images of Hela cells after treatment with DPL/siRNA under different incubation time. The siRNA was labeled with fluorescein amidite (FITC). The embedded scale bars correspond to 10 μm. (D) Fluorescence imaging of tumor-bearing mice in vivo after DPL/siRNA injection via tail vein. Reproduced with permission from Sun et al. (2020). Copyright 2020 American Chemical Society.