Table 3.

GEE parameter estimates for the association of degree of hematuria during follow-up with eGFR during follow-up

	Average eGFR decline per degree increase in hematuria
Adjusted for	eGFR decline (mL/min/1.73 m2)	95% Lower	95% Upper	P-value
Time	−1.1192	−1.6834	−0.5551	<0.001
Time + estimated proteinuria	−0.7432	−1.3567	−0.1297	0.018
Time + M	−1.1248	−1.7069	−0.5427	<0.001
Time + E	−1.0750	−1.6281	−0.5220	<0.001
Time + S	−1.0712	−1.6287	−0.5138	<0.001
Time + T	−1.1346	−1.7087	−0.5606	<0.001
Time + C	−1.1214	−1.6798	−0.5630	<0.001
Time + RASB	−1.1337	−1.7277	−0.5396	<0.001
Time + immunosuppression	−1.1532	−1.7374	−0.5690	<0.001
Time + RASB, immunosuppression	−1.1642	−1.7734	−0.5550	<0.001
Time + estimated proteinuria + T	−0.8122	−1.4358	−0.1886	0.011

n = 390 laboratory measures available between biopsy date and last follow-up or ESRD, among 72 patients.

GEE models using time-dependent predictors were modeled as main effects, and time-independent predictors (MEST-C scores) were considered along with an interaction term for time in order to estimate a within-subjects effect.

P-values in bold denote significance at the 0.05 level.