Table 5.
Association between patient characteristics at baseline and incidence of ESRD
Baseline variables | HR | 95% Lower | 95% Upper | P-value |
---|---|---|---|---|
Demographics | ||||
Age, per year | 1.038 | 0.996 | 1.081 | 0.078 |
Sex (female versus male) | 0.667 | 0.166 | 2.677 | 0.57 |
Laboratory measures at baseline | ||||
Serum creatinine, per 1 mg/dL | 4.501 | 1.940 | 10.443 | 0.001 |
eGFR, per 10 mL/min/1.73 m2 | 0.294 | 0.127 | 0.680 | 0.004 |
Systolic BP, per 10 mmHg | 1.726 | 1.294 | 2.303 | <0.001 |
Diastolic BP, per 10 mmHg | 0.928 | 0.480 | 1.796 | 0.83 |
Estimated proteinuria, per 0.5 g | 1.375 | 1.154 | 1.639 | <0.001 |
Baseline hematuria, per degreea (ordinal) | 0.853 | 0.639 | 1.140 | 0.28 |
Hematuria (≥3 RBCs/hpf versus <3 RBCs/hpf) | 1.458 | 0.180 | 11.811 | 0.72 |
Histology at biopsy | ||||
M (1 versus 0) | 1.368 | 0.171 | 10.971 | 0.77 |
E (1 versus 0) | 0.761 | 0.158 | 3.678 | 0.73 |
S (1 versus 0) | 4.643 | 0.578 | 37.287 | 0.15 |
T (≥1 versus 0) | 12.208 | 1.525 | 97.707 | 0.018 |
C (≥1 versus 0) | 0.986 | 0.246 | 3.944 | 0.98 |
RASB | 1.242 | 0.333 | 4.633 | 0.75 |
Degree of hematuria treated as ordinal variable with the following levels: as 0, <3, 3–10, 11–20, 21–30, 31–40, 41–50, 51–100, >100.
P-values in bold denote significance at the 0.05 level.
BP, blood pressure.