Table 1.
Baseline characteristics in patients with at least two visits with eGFR-MDRD and overall symptom score available during first year of pre-dialysis
| Symptom number and eGFR-MDRD available for at least one visit during 1-year pre-dialysis (n = 1109)a | Symptom severity and eGFR-MDRD available for at least one visit during 1-year pre-dialysis (n = 1019)b | |
|---|---|---|
| Sex, male | 764 (68.9) | 698 (68.5) |
| Age, years | 75.9 (70.5–80.8) | 75.7 (70.2–80.5) |
| Ethnicity | ||
| Caucasian | 1087 (98.4) | 1000 (98.4) |
| Black | 6 (0.5) | 6 (0.6) |
| Other | 12 (1.1) | 10 (1.0) |
| Primary kidney disease | ||
| Glomerular disease | 106 (9.6) | 99 (9.7) |
| Tubulo-interstitial disease | 95 (8.6) | 89 (8.7) |
| Diabetes mellitus | 214 (19.3) | 187 (18.4) |
| Hypertension | 385 (34.7) | 361 (35.4) |
| Other/unknown | 309 (27.9) | 283 (27.8) |
| Educational levelc | ||
| No | 27 (2.5) | 24 (2.4) |
| Low | 308 (28.8) | 266 (27.0) |
| Intermediate | 544 (50.9) | 510 (51.8) |
| High | 154 (14.4) | 151 (15.3) |
| Other | 36 (3.4) | 34 (3.5) |
| Marital status, married or living together | 714 (66.0) | 662 (66.6) |
| Diabetes mellitus, yesd | 449 (41.3) | 404 (40.4) |
| Hypertension, yese | 991 (92.2) | 919 (92.6) |
| Cerebrovascular disease, yes | 168 (15.5) | 152 (15.3) |
| Myocardial infarction, yes | 202 (18.5) | 185 (18.5) |
| Malignancy, yes | 228 (21.2) | 210 (21.1) |
| Psychiatric disease, yes | 86 (7.9) | 75 (7.5) |
| BMI, kg/m² | 28.2 (±5.3) | 28.2 (±5.3) |
| eGFR baseline, mL/min/1.73 m² | 18.9 (±5.4) | 18.8 (±5.3) |
| Serum albumin, g/L | 37.6 (±5.9) | 37.6 (±5.8) |
| Haemoglobin, mmol/L | 7.2 (±0.9) | 7.2 (±0.9) |
| Proteinuria, g/24 h | 1.5 (0.5–5.0) | 1.5 (0.5–5.4) |
Values are given as frequency (percentage), mean (±SD) or median (IQR), as appropriate.
Missings: 0.4% ethnicity, 0.9% educational level, 2.5% marital status, 1.9% diabetes, 3.1% hypertension, 2.4% cerebrovascular disease, 1.8% myocardial infarction, 2.8% malignancy, 2.3% psychiatric disease, 6.6% BMI, 9.8% albumin, 2.1% haemoglobin, 71.8% proteinuria.
Missings: 0.3% ethnicity, 2.5% marital status, 3.3% educational level, 1.9% diabetes, 2.6% hypertension, 2.3% cerebrovascular disease, 1.8% myocardial infarction, 2.4% malignancy, 2.2% psychiatric disease, 6.8% BMI, 9.7% albumin, 2.1% haemoglobin, 71.9% proteinuria.
Defined as: low, no education or primary school only; intermediate, primary and secondary school; high, academic education.
Defined as the presence of diabetes mellitus as primary kidney disease or a history of diabetes mellitus, both Type I and Type II.
Defined as either the presence of hypertension as primary kidney disease or a history of hypertension.