Table 3.
Effect per unit lower eGFR-MDRD at baseline on annual change in symptom number and severity
| Symptom number (n = 1104) | Symptom severity (n = 1015) | |
|---|---|---|
| Mean annual increase (95% CI) | 0.76 (0.30; 1.21) | 3.00 (1.41; 4.59)* |
| Extra increase per unita lower kidney function at baseline | ||
| Unadjusted | 0.02 (−0.08; 0.11) | −0.03 (−0.37; 0.30) |
| Adjustedb | 0.08 (−0.01; 0.17) | 0.21 (−0.13; 0.55) |
a
One unit is 1 mL/min/1.73 m2.
b
Adjusted for: age, sex, ethnicity, country of residence, educational level, diabetes mellitus, cerebrovascular disease, myocardial infarction, hypertension, malignancy, psychiatric disease, BMI, primary kidney disease, haemoglobin and proteinuria at baseline.
*
P < 0.05.