Fig. 3.

Collagen VI immunofluorescence in UCMD dermal fibroblasts (permeabilised (A) and non-permeabilised (B) conditions according to Hicks et al. (2008); CTRL –normal control, which has an abundance of well-organized collagen VI microfibrils showing a linear and unidirectional trend; III:1; III:2, III:3 –significant collagen VI rarefication with stained single extracellular microfibrils and intracellular protein retention were noticed in most cells. Dermal fibroblasts immunostained for matrix-deposited collagen VI (red) and with the nuclear stain DAPI (blue). Scale bar 50μm.