Table 1.
Demographic, clinical, blood biochemistry, and MRI characteristics of patients with MCI on their initial visit
| All MCI | Followed-up | |
| (n = 38) | MCI (n = 24) | |
| Sex (M/F) | 13/25 | 9/15 |
| Age | 77.4±5.6 | 76.7±5.8 |
| Education (y) | 13.4±2.3 | 13.5±2.6 |
| MMSE | 27.3±1.6 | 27.2±1.6 |
| FAB | 13.0±2.2 | 12.9±2.3 |
| TMT-A (s) | 52.7±20.8 | 50.3±20.0 |
| TMT-B (s) | 156.9±80.8 | 155.4±83.4 |
| WMS-R-Logical Memory (immediate) | 13.6±6.7 | 14.4±7.0 |
| VF (category) | 14.5±3.4 | 14.5±3.5 |
| GDS-15 | 3.8±3.1 | 4.2±3.7 |
| Cystatin C (mg/L) | 1.0±0.2 | 1.0±0.2 |
| 25(OH)VitD (ng/ml) | 25.0±11.9 | 25.7±13.4 |
| Homocysteine (nmoL/mL) | 10.5±3.5 | 10.5±3.1 |
| PVH volume (mm3) | 8,905±7,678 | 10,450±9,087 |
| DWMH volume (mm3) | 4,529±9,223 | 5,839±11,495 |
| PVH volume ratio (%) | 0.70±0.60 | 0.76±0.66 |
| DWMH volume ratio (%) | 0.30±0.70 | 0.43±0.85 |
| Hypertension, n (%) | 21 (55) | 12 (50) |
| Diabetes mellitus, n (%) | 7 (18) | 4 (17) |
| Dyslipidemia, n (%) | 20 (53) | 10 (42) |
| Coronary artery disease, n (%) | 3 (8) | 1 (4) |
| Antihypertensives, n (%) | 20 (53) | 12 (50) |
| Antidiabetic medications, n (%) | 3 (8) | 2 (8) |
| Statins, n (%) | 11 (29) | 5 (21) |
MMSE, Mini-Mental State Examination; FAB, Frontal Assessment Battery; TMT, Trail Making Test; WMS-R, Wechsler Memory Scale-Revised; VF, verbal fluency; GDS, Geriatric Depression Scale; 25(OH)VitD, 25-hydroxyvitamin D; PVH, periventricular hyperintensities; DWMH, deep white matter hyperintensities; MCI, mild cognitive impairment.