Table 4.
Initial PVH vol. ratio | Changes in PVH vol. ratio | Initial DWMH vol. ratio | Changes in DWMH vol. ratio | |||||
Changes in measurement | Coefficient | P | Coefficient | P | Coefficient | P | Coefficient | P |
MMSE | –0.32 | 0.13 | –0.2 | 0.35 | –0.15 | 0.5 | –0.5* | 0.01 |
FAB | 0.27 | 0.21 | 0.003 | 0.99 | –0.02 | 0.93 | 0.11 | 0.62 |
TMT-A | 0.07 | 0.76 | 0.25 | 0.26 | –0.08 | 0.73 | 0.08 | 0.74 |
TMT- B | 0.18 | 0.43 | –0.04 | 0.85 | 0.5* | 0.02 | 0.33 | 0.14 |
WMS-R | 0.35 | 0.1 | 0.41 | 0.05 | 0.2 | 0.37 | 0.29 | 0.17 |
VF | –0.35 | 0.12 | –0.43 | 0.05 | –0.21 | 0.36 | –0.46* | 0.04 |
GDS-15 | –0.11 | 0.61 | –0.28 | 0.2 | 0.4 | 0.06 | 0.02 | 0.93 |
Cystatin C | –0.14 | 0.51 | –0.25 | 0.25 | 0.55** | 0.005 | 0.18 | 0.41 |
*p < 0.05, significant correlation with the initial ratio or ratio changes of DWMH volume to ICV. **p < 0.01, significant correlation with the initial ratio of DWMH volume to ICV. MMSE, Mini-Mental State Examination; FAB, Frontal Assessment Battery; TMT, Trail Making Test; WMS-R, Wechsler Memory Scale-Revised; VF, verbal fluency; GDS, Geriatric Depression Scale; PVH, periventricular hyperintensities; DWMH, deep white matter hyperintensities; ICV, intracranial volume.