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The T-test results for VNs’ comparison between pathogenic and non-pathogenic positions in each set of sequences
| Pathogenic | Non-Pathogenic | T-test | ||||||
| Mean | Median | STD | Mean | Median | STD | t-Value | p-Value | |
| BRCA1 BLAST | 189.23 | 181.00 | 48.39 | 210.82 | 205.00 | 49.76 | -8.57 | 8.37e-17 |
| BRCA1 Orthologs | 104.86 | 112.00 | 48.13 | 133.05 | 140.00 | 47.40 | -11.32 | 4.31e-27 |
| BRCA2 BLAST | 154.48 | 157.00 | 34.98 | 169.81 | 172.00 | 36.51 | -10.02 | 2.66e-22 |
| BRCA2 Orthologs | 97.03 | 104.00 | 46.37 | 117.66 | 125.00 | 44.87 | -10.25 | 3.60e-23 |
