Table 2.

Zero-inflated negative binomial model for predicting number of SAEs

Part 1: logistic part for excessive zero (ie., having no SAE)
Parameter	Odds Ratio (OR)	95% Confidence Interval	p-value
Age at first donepezil	0.972	(0.929, 1.017)	0.2181
Male vs Female	1.739	(0.711, 4.255)	0.2256
Race/Ethnicity
Hispanic vs NHW	0.204	(0.079, 0.531)	0.0011
NHB vs NHW	0.659	(0.232, 1.867)	0.4321
Number of donepezil prescription	0.027	(0.003, 0.231)	0.0010
Number of months on donepezil	0.966	(0.834, 1.119)	0.6448
Chronic conditions * (Only p < 0.05 are shown here)
Anemia	0.268	(0.097, 0.74)	0.0110
Ischemic Heart Disease	0.122	(0.029, 0.52)	0.0044
Part 2: negative binomial part
Parameter	Estimate	95% Confidence Interval	p-value
Age at first donepezil	0.998	(0.988, 1.007)	0.5995
Male vs Female	1.072	(0.867, 1.326)	0.5213
Race/Ethnicity
Hispanic vs NHW	0.874	(0.699, 1.093)	0.2369
NHB vs NHW	1.285	(1.042, 1.584)	0.0190
Number of donepezil prescription	1.104	(1.071, 1.139)	<.0001
Number of months on donepezil	1.023	(1.017, 1.03)	<.0001
Chronic conditions * (Only p < 0.05 are shown here)
Chronic obstructive pulmonary disease (COPD)	1.397	(1.134, 1.719)	0.0016
Hyperlipidemia	0.756	(0.624, 0.916)	0.0042
Hypertension	1.517	(1.202, 1.914)	0.0004
Anxiety disorder	1.368	(1.115, 1.679)	0.0027