Table 4.

Population size, model adjusted mean number of SAEs, and mGIST when dropping individual exclusion criteria, independently, stratified by eligible vs. non-Eligible group.

	Eligible		non-Eligible
Independently dropping individual exclusion criteria	Population Size (N)	# of Mean SAEs	Population Size (N)	# of Mean SAEs	sGIST*	mGIST
00.Original	373	0.66	1642	0.99	.	0.062
The lowest sGIST scores after dropping these exclusion criteria
01.Drop Cardiac disease	503	0.67	1512	1.01	0.578	0.078
02.Drop Depression	431	0.68	1584	0.99	0.716	0.074
03.Drop Uncontrolled Hypertension	431	0.83	1584	0.95	0.768	0.074
The highest sGIST scores after dropping these exclusion criteria
13.Drop Drug use disorders	378	0.66	1637	0.99	0.955	0.062
14.Drop Alcohol use disorders	378	0.66	1637	0.99	0.962	0.063
15.Drop Uncontrolled diabetes	378	0.66	1637	0.99	0.964	0.062
16.Drop Use antidepressants	373	0.66	1642	0.99	0.991	0.062

^*sGIST score of the specific exclusion criterion before dropping the exclusion criterion.