Table 5.

Population size, model adjusted mean number of SAEs, and mGIST when dropping combined individual exclusion criteria, sequentially, stratified by eligible vs. non-Eligible group.

	Eligible		non-Eligible
Subsequently dropping criterion	Population Size (N)	# of Mean SAEs	Population Size (N)	# of Mean SAEs	mGIST
00.Original	373	0.66	1642	0.99	0.062
01.Drop Cardiac disease	503	0.67	1512	1.01	0.078
02.Drop Depression	603	0.70	1412	1.02	0.096
03.Drop Uncontrolled Hypertension	744	0.83	1271	0.98	0.120
04.Drop Dementias other than AD	865	0.82	1150	1.00	0.141
05.Drop Sleep disorder	972	0.85	1043	1.00	0.157
06.Drop Cancer	1101	0.83	914	1.04	0.175
07.Drop Visual/Hearing Impairment	1206	0.85	809	1.04	0.194
08.Drop fecal/urinary incontinence	1320	0.90	695	0.97	0.214
09.Drop Conditions affect absorption	1413	0.93	602	0.92	0.232
10.Drop Parkinsons disease	1499	0.91	516	0.97	0.241
11.Drop Other AD treatments	1575	0.91	440	0.99	0.256
12.Drop Schizophrenia	1645	0.90	370	1.04	0.260
13.Drop Drug use disorders	1703	0.91	312	1.01	0.269
14.Drop Alcohol use disorders	1778	0.94	237	0.80	0.280
15.Drop Uncontrolled diabetes	1846	0.94	169	0.78	0.290
16.Drop Use antidepressants	1856	0.95	159	0.69	0.292