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. 2021 Apr 27;14(1):15–48. doi: 10.1007/s12602-021-09791-7

Table 3.

List of patents related to encapsulated probiotics and their applications

Company/assignee Title of the patent References
Durkee Industrial Foods Corp., Iselin, NJ Encapsulated yeast

US4719114A

United States, 12 January 1988

General Mills, Inc., Minneapolis, MN (US) Embedding and encapsulation of controlled-release particles

US6190591B1

United States, 20 February 2001

Balchem Corp., NY, US Solvent released encapsulated yeast

US6616954B1

United States, 9 September 2003

Societe des Produits Nestle SA and Nestle SA, Vevey (CH) Probiotic delivery system

EP1482811A1

European Patent Office, 8 December 2004

Commonwealth Scientific & Industrial Research Organisation, Campbell, ACT (AU) Probiotic storage and delivery

WO2005030229A1

WIPO (PCT), 7 April 2005

Mars Inc., US Foodstuff

US20050079244A1

United States, 14 April 2005

Canacure Corp., ON, CA Stable probiotic microsphere compositions and their methods of preparation

US20050266069A1

United States, 1 December 2005

General Mills, Inc., Minneapolis, MN (US) Cultures encapsulated with chocolate food products coated with chocolate and methods of preparation

WO2006007470A1

WIPO (PCT), 19 January 2006

Lallemand S.A., Blagnac (FR)Current Assignee: Danstar Ferment AG Particles containing coated living micro-organisms, and method for producing the same

US7157258B2s

United States, 2 January 2007

Later, 12 June 2009 the patent assigned to Danstar Ferment AG

Attune Foods, US Probiotic food, the process for its preparation and dietary regimen

WO2007081981A2

WIPO (PCT), 19 July 2007

Escola Superior De Biotecnologia, Porto (PT) Pre-fermented symbiotic matrix based on a cereal suspension with encapsulated probiotics, manufacture process, and corresponding utilization

WO2008041876A2

WIPO (PCT), 10 April 2008

Etherton Law Group, Llc., US Method of using topical probiotics for the inhibition of surface contamination by a pathogenic microorganism and composition therefor

US20080107699A1

United States, 8 May 2008

General Mills, Inc., Minneapolis, MN (US) Cultures encapsulated with compound fat breakfast cereals coated with compound fat and methods of preparation

US20080305210A1

United States, 11 December 2008

Ganeden Biotech, Inc. US Baked goods

WO2009029267A1

WIPO (PCT), 5 March 2009

Nizo Food Research B.V., (NL) Protein-based probiotic encapsulates

WO2009070012A1

WIPO (PCT), 4 June 2009

Probiotical S.P.A., Novara, IT Chocolate flavored probiotic supplement

WO2010086705A2

WIPO (PCT), 5 August 2010

DeGama Products, Ltd (Grand Caymon) Process for preparing bakeable probiotic food

US20100303962A1

United States, 2 December 2010

The Procter & Gamble Company, Ohio, (US) A method of promoting GI health using a combination of a probiotic microorganism and chocolate

WO2010151637A1

WIPO (PCT), 29 December 2010

DeGama Products, Ltd (Grand Caymon) Heat resistant probiotic compositions and healthy food comprising them

US20110008493A1

United States, 13 January 2011

Erber AG, Herzogenburg (AT) Probiotic health or fitness promoting human or animal foodstuff and/or drinking water additive and use thereof

US8101170B2

United States, 24 January 2012

R.P Scherer Technologies, Llc., Carson City, Nevada (US) Process of manufacturing a stable softgel capsule containing microencapsulated probiotic bacteria

WO 2012021432A2

WIPO (PCT), 16 February 2012

Nestec S.A., Vevey (CH) A consumable product containing probiotics

US8263146B2

United States, 11 September 2012

Advanced BioNutrition Corporation, Columbia, MD (US) Dry food product containing live probiotic

US8460726B2

United States, 11 June 2013

Dow Global Technologies Llc., Michigan (US) Probiotic-containing particles having improved probiotic stability when in aqueous formulations

WO2013188626A2

WIPO (PCT), 19 December 2013

Centro Nacional De Tecnología Y SeguridadAlimentaria, Laboratorio Del Ebro, Universidad De Navarra, Navarra (ES) Microparticles for the encapsulation of probiotics, preparation and uses thereof

WO2014006261A3

WIPO (PCT), 9 January 2014

Vita-Herb Nutriceuticals, Inc., Placentia, CA (US) Prebiotic and preservative uses of oil-emulsified probiotic encapsulations

US8846082B2

United States, 30 September 2014

Commonwealth Scientific and Industrial Research Organization (CSIRO) (AU) Probiotic storage and delivery

US8871266B2

United States, 28 October 2014

University Of Saskatchewan (CA) Microcapsules containing probiotics and methods of making the same

WO2015019307A1

WIPO (PCT), 12 February 2015

Advanced BioNutrition Corporation, Columbia, MD (US) The delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides, and polyols in a glass form and methods of making the same

US8968721B2

United States, 3 March 2015

ProGel Pty Ltd, Brisbane (AU) Microparticles comprising a probiotic, cross-linkable reagent, a denatured protein, polyol plasticizer, and trehalose

US20150313844A1

United States, 5 November 2015

Goodman Fielder New Zealand Ltd., Auckland (NZ) Probiotic fortified food products and methods of manufacture

WO2015199552A1

WIPO (PCT), 30 December 2015

Ayanda Group As, Oslo (NO) and Golding, Louise, London (GB) An improved process for producing a softgel capsule comprising viable probiotic bacteria and a soft gel capsule comprising viable probiotic bacteria having a long shelf life

WO2016038355A1

WIPO (PCT), 17 March 2016

DeGamaBerrier Ltd., Grand Cayman (KY) Composition and method for improving stability and extending the shelf life of probiotic bacteria and food products thereof

US20160360777A1

United States, 15 December 2016

Vesale Pharma S.A. (BE) and Brace GmbH (DE) Microencapsulated probiotic substance and process of manufacture

US9554590B2

United States, 31 January 2017

Massachusetts Institute of Technology, Cambridge, MA (US) Ph-responsive mucoadhesive polymeric encapsulated microorganisms

US20170165201A1

United States, 15 June 2017

FundacionTecnalia Research & Innovation, Edificio, Derio (ES) Multilayer probiotic microcapsules

WO2017137496A1

WIPO (PCT), 17 August 2017

PepsiCo, Inc., Purchase, NY (US) and Massey University, Palmerston North (NZ) Encapsulation system for the protection of probiotics during processing

US9788563B2

United States, 17 October 2017

Mead Johnson Nutrition Co., Chicago, IL (US) Probiotic stabilization

US20170296600A1

United States, 19 October 2017

Uab " Probiosanus ", Vilnius (LT) Composition and method for increase of survival and stabilization of probiotic bacteria in detergent-based compositions of personal hygiene and domestic products

US20180360707A1

United States, 20 December 2018

Hill’s Pet Nutrition, Inc., Topeka, KS, (US) Pet food compositions including probiotics and methods of manufacture and use thereof

US20190142032A1

United States, 16 May 2019

Centro Nacional De Tecnología Y Seguridad Alimentaria (ES) and Universidad de Navarra (ES) Microparticles for encapsulating probiotics, production, and uses thereof

US20190192439A1

United States, 27 June 2019