. 2021 Mar 20;41(3):391–398. [Article in Chinese] doi: 10.12122/j.issn.1673-4254.2021.03.11

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数据ACTG175的亚组识别结果

Subgroup analysis of dataACTG175

Object	Univariate, Eq_ex	Penalized, Eq_in
Univariate, Eq_ex: The univariate model excluding main effect; Penalized, Eq_in: The penalized model including main effect; Overall test: The 1st stage of biomarker adaptive design（α₁ =0.03）; Subgroup test: The 2st stage of biomarker adaptive design（α₂ =0.02）. ^*P value of Logrank test, ^§Median survival time: Days (group size or subgroup size).
Overall test (P-value) ^*	0.181	0.181
Subgroup test (P-value) ^*	0.369	0.549
ZDV+ddI^§	1014 (522)	1014 (522)
ddI^§	1000 (559)	1000 (559)
ZDV+ddI g+^§	1048.5 (270)	1015(141)
ZDV+ddI g-^§	992.5 (252)	1013(381)
ddI g+^§	1020 (293)	999 (183)
ddI g-^§	991(266)	1001 (376)