1.
2型糖尿病患者的基线资料
Clinical and biochemical data of type 2 diabetic patients with and without DR
| Variable | NDR (n=182) | DR (n=109) | T value (vswvalue, χ2 value) | P |
| Note: T2DM: Type 2 diabetes; DR: Diabetic retinopathy; HbA1c: Glycosylated hemoglobin; FBG: Fasting blood glucose; HOMA-IR: Homeostasis model assessment for insulin resistance; SBP: Systolic blood pressure; DBP: Diastolic blood Pressure; TC: Total cholesterol; LDL-C: Low density lipoprotein cholesterol; HDL-C: High density lipoprotein cholesterol; TG: Triglyceride; UA: uric acid; BMI: Body mass index; Scr: Serum creatinine; UA: uric acid; APOA: Apolipoprotein A; APOB: Apolipoprotein B; CRP: C-reactive protein; CTRP9: C1q tumour necrosis factor-related protein 9. | ||||
| Gender (male/female) | 112/70 | 50/59 | 6.78 | 0.009 |
| Age (year) | 56±16 | 60±13 | -2.27 | 0.024 |
| History of hypertension | 85(46.70%) | 75 (68.81%) | 13.45 | < 0.001 |
| SBP (mmHg) | 135.2±18.6 | 147.6±23.5 | -4.98 | < 0.001 |
| DBP (mmHg) | 81.1±11.8 | 80.6±14.1 | 0.36 | 0.719 |
| Duration of T2DM | 6.00 (1.00-10.00) | 13.00(10.00-20.00) | -6.94 | < 0.001 |
| BMI (kg/m2) | 26.0±3.6 | 25.1±3.0 | 2.03 | 0.030 |
| HbA1C (%) | 9.45 (7.80-11.12) | 8.80(7.60-11.30) | -1.99 | 0.926 |
| FBG (mmol/L) | 8.35(7.23-9.47) | 8.50(7.30-10.40) | -1.53 | 0.250 |
| Insulin (μU/mL) | 8.30 (7.10-9.40) | 11.40 (9.80-13.80) | -10.87 | < 0.001 |
| HOMA-IR | 3.10 (2.40-3.90) | 4.30 (3.50-5.60) | -7.95 | < 0.001 |
| Serum urea (mmol/L) | 5.28 (4.29-6.75) | 6.55 (5.03-11.60) | -1.79 | < 0.001 |
| Scr (μmol/L) | 73.08 (65.02-87.21) | 86.80 (73.00-129.50) | -5.79 | < 0.001 |
| UA (μmol/L) | 348.5 (304.0-431.00) | 401.0 (327.0-481.0) | -2.11 | 0.024 |
| TG (mmol/L) | 1.55 (1.05-2.59) | 1.85 (0.96-2.55) | 1.43 | 0.857 |
| TC (mmol/L) | 4.75 (3.90-5.60) | 4.90 (3.90-6.27) | -1.90 | 0.075 |
| HDL-C (mmol/L) | 0.94 (0.81-1.12) | 1.01 (0.83-1.17) | -1.38 | 0.110 |
| LDL-C (mmol/L) | 3.14±0.92 | 3.32±1.12 | -1.48 | 0.139 |
| APOA(g/L) | 1.13 (0.98-1.26) | 1.12 (1.01-1.28) | -0.58 | 0.416 |
| APOB(g/L) | 0.94 (0.74-1.10) | 0.94 (0.73-1.24) | -0.81 | 0.648 |
| CRP (mg/dL) | 0.58 (0.22-1.54) | 1.13 (0.58-1.99) | -0.40 | 0.003 |
| Adiponectin (μg/mL) | 7.25 (5.95-8.68) | 5.95 (5.04-6.79) | 8.15 | < 0.001 |
| CTRP9 (pg/mL) | 122.3 (110.8-134.0) | 153.5 (140.0-161.0) | -12.27 | < 0.001 |