2.
血清CTRP9浓度与临床特征的相关性
Correlation between serum CTRP9 concentration and clinical parameters
| CTRP9 | Variable | T2DM (n=291) | DR (n=109) | |||
| r | P | r | P | |||
| T2DM: Type 2 diabetes; DR: Diabetic retinopathy; HbA1c: Glycosylated hemoglobin; FBG: Fasting blood glucose; HOMA-IR: Homeostasis model assessment for insulin resistance; SBP: Systolic blood pressure; DBP: Diastolic blood Pressure; TC: Total cholesterol; LDL-C: Low density lipoprotein cholesterol; HDL-C: High density lipoprotein cholesterol; TG: Triglyceride; UA: uric acid; BMI: Body mass index; Scr: Serum creatinine; UA: Uric acid; APOA: Apolipoprotein A; APOB: Apolipoprotein B; CRP: C-reactive protein; CTRP9: C1q tumour necrosis factor-related protein. | ||||||
| Age (years) | 0.06 | 0.303 | 0.14 | 0.136 | ||
| BMI (kg/m2) | 0.25 | < 0.001 | 0.39 | < 0.001 | ||
| Duration of T2DM | 0.25 | < 0.001 | 0.07 | 0.422 | ||
| SBP (mmHg) | 0.17 | 0.004 | 0.10 | 0.304 | ||
| DBP (mmHg) | -0.02 | 0.792 | -0.03 | 0.765 | ||
| HbA1C (%) | 0.04 | 0.591 | -0.12 | 0.223 | ||
| FBG (mmol/L) | 0.13 | 0.031 | 0.02 | 0.804 | ||
| Insulin (μU/mL) | 0.34 | < 0.001 | 0.33 | < 0.001 | ||
| HOMA-IR | 0.32 | < 0.001 | 0.22 | 0.019 | ||
| Serum urea (mmol/L) | 0.11 | 0.061 | 0.13 | 0.166 | ||
| Scr (μmol/L) | 0.13 | 0.027 | 0.16 | 0.095 | ||
| UA (μmol/L) | -0.02 | 0.666 | -0.15 | 0.121 | ||
| TG (mmol/L) | 0.06 | 0.289 | 0.07 | 0.479 | ||
| TC (mmol/L) | 0.09 | 0.143 | -0.11 | 0.233 | ||
| HDL-C (mmol/L) | 0.16 | 0.007 | -0.05 | 0.638 | ||
| LDL-C (mmol/L) | 0.05 | 0.358 | -0.08 | 0.390 | ||
| APOA (g/L) | 0.13 | 0.027 | 0.01 | 0.970 | ||
| APOB (g/L) | 0.10 | 0.118 | 0.01 | 0.979 | ||
| CP (mg/dL) | 0.21 | < 0.001 | 0.39 | < 0.001 | ||
| Adiponectin (μg/mL) | -0.27 | < 0.001 | -0.23 | 0.017 | ||
| Stage of DR | - | - | 0.48 | < 0.001 | ||