3.

KEGG代谢途径差异

Differential metabolic pathways between diabetic and healthy groups

KEGG metabolic pathway	0: mean proportion (%)	1: mean proportion (%)	P(corrected)
Renal cell carcinoma	0.0055	0.0085	0.0003
Styrene degradation	0.0152	0.0215	0.0006
Lipopolysaccharide biosynthesis	0.2471	0.3076	0.0009
Lipopolysaccharide biosynthesis proteins	0.3472	0.4145	0.0012
Tetracycline biosynthesis	0.1490	0.1320	0.0015
Cell motility and secretion	0.1595	0.1756	0.0021
Glycosyltransferases	0.3340	0.3577	0.0039
Arachidonic acid metabolism	0.0282	0.0347	0.0056
Sulfur metabolism	0.2594	0.2742	0.0059
Pathways in cancer	0.0478	0.0512	0.0063
Protein folding and associated processing	0.6069	0.6296	0.0084
Methane metabolism	1.3025	1.2490	0.0087
Metabolism of cofactors and vitamins	0.1021	0.1108	0.0092
Glycerophospholipid metabolism	0.5505	0.5283	0.0117
Prenyltransferases	0.3206	0.3329	0.0119
Phenylalanine metabolism	0.1913	0.2022	0.0140
Isoquinoline alkaloid biosynthesis	0.0614	0.0658	0.0146
Protein processing in endoplasmic reticulum	0.0650	0.0710	0.0149
Glyoxylate and dicarboxylate metabolism	0.4932	0.5146	0.0159
Mineral absorption	0.0053	0.0069	0.0166
RNA transport	0.1420	0.1318	0.0186
Nitrogen metabolism	0.6962	0.7196	0.0190
N-Glycan biosynthesis	0.0250	0.0283	0.0194
D-Arginine and D-ornithine metabolism	0.0021	0.0031	0.0249
Polycyclic aromatic hydrocarbon degradation	0.1150	0.1097	0.0257
Glutathione metabolism	0.2033	0.2142	0.0281
Transporters	6.4913	6.1660	0.0306
Pantothenate and CoA biosynthesis	0.6276	0.6426	0.0321
Cysteine and methionine metabolism	0.9269	0.9424	0.0324
Carbohydrate digestion and absorption	0.0144	0.0173	0.0332
Tropane, piperidine and pyridine alkaloid biosynthesis	0.1211	0.1258	0.0359
Novobiocin biosynthesis	0.1344	0.1386	0.0371
Streptomycin biosynthesis	0.3026	0.3177	0.0439
Plant-pathogen interaction	0.1549	0.1487	0.0443
Citrate cycle	0.5965	0.6258	0.0443
Butirosin and neomycin biosynthesis	0.0593	0.0602	0.0494